One of Cytovance’s core services is recombinant protein drug substance production derived from mammalian cell culture. The key to our expression success is our talented team’s world-class cell line development services that help select the perfect clone for each product.
With more than 20 years in mammalian-based protein production, our experience and culture of ingenuity offer significant benefits to therapeutic developers. Using the trusted ThermoFisher Scientific FreedomTM CHO S system, we have developed an iterative development process that starts with a pool of thousands of transfected clones that are subsequently narrowed down to identify your product’s ideal candidates. We find the right clone through single-cell cloning via the Namocell and productivity and clonal stability studies using shake flasks or Ambr® 15 mini bioreactors. With the seamless integration of analytics during this process, our approach can enhance the transferability from R&D to Manufacturing and result in multiple benefits for our clients.
Deep experience in mammalian cell line development has given our team a thorough understanding of critical parameters through the development process that can affect productivity at a large scale. The result is a highly predictable process, supported by strong data and critical insights.
Take your productivity to the next level with our process development experts.
Robust analytical method development or transfer personalized for your mammalian-derived biologic.
Benefit from our full-service CGMP facility from cell banks to production with up to 2,000L capacity.
