From mammalian cell banking to 2,000L single-use bioreactor runs, Cytovance has an unrivaled track record in cGMP mammalian manufacturing. At this stage, the exceptional work formalized during process development is executed under strict oversight in our state-of-the-art facilities and your product is one step closer to the clinic.
Mammalian-derived cell culture manufacturing is a core capability of Cytovance. Our extensive experience combined with our deep technical expertise has enabled the clinical translation of a diverse portfolio of complex protein therapeutics in a wide array of application areas including oncology, infectious diseases, diabetes, and arthritis. Flexibility and producing critical data is key to our approach. From full-service cell line and process development to tech transfer for GMP cell culture manufacturing or a facilitated timeline with the Cytovance platform, we can be responsive to meet your molecule’s needs and provide seamlessly integrated analytical support. Cytovance currently offers an attractively licensed and widely trusted ThermoFisher Scientific Freedom™ CHO-S-based manufacturing platform, which is suitable for either antibody or non-antibody-based proteins.
Through our experience in establishing the Cytovance mammalian and monoclonal antibody production platform, we have gained a thorough understanding of critical parameters through the development process that can affect productivity at large scale. The result is an experienced team that is able to produce a highly predictable and robust process for your molecule with a significant reduction in development time to manufacturing.
To keep your molecule moving forward we have a range of cGMP-qualified bioreactor scales that provide flexibility around demand during varying stages of the product life cycle.
Our manufacturing facilities house multiple scales of mammalian-based stir tank single-use-based bioreactors from 250L to 2000L. When coupled with platformed cell culture and purification processes, we can ensure maximal purity, potency, and yields of your mammalian-derived biologic while maintaining the highest level of regulatory compliance.
Complete mammalian clone selection, clonal stability, and banking services tailored to your requirements.
Take your productivity to the next level with our process development experts.
Robust analytical method development or transfer personalized for your mammalian-derived biologic.
