Mammalian Process Development

Rapid and Flexible Progression to Manufacturing

Our dedicated cell culture process development experts help optimize the performance of your cell culture production process. They work diligently to design fast, robust, and efficient processes that will reliably get your molecule to the clinic faster.

Your Experienced Partner in the Mammalian Space

With decades of experience in developing scalable processes for mammalian production platforms, we provide deep technical expertise and time-tested methods. Collaborating closely with our Manufacturing Sciences & Technology and Manufacturing teams, our cell culture process development team is skilled at providing a complete process design that will maximize performance and be scalable to meet future commercial requirements. Through a combination of in-process screening, developed analytical methods, media optimization, and systematic optimization of bioreactor parameters, we can develop and execute a robust process while saving valuable time and resources.

Customized Approach

As your responsive CDMO partner, we have flexible options that build on the work you’ve already accomplished. Each project is customized to match the unique scope and clinical phase of your product needs. In-house platform processes further enable efficient movement from development into commercialization. Whether it be starting from cell line development or GMP manufacturing process transfer, we have a scenario that can fit your requirements and the ingenuity to support you on the path to patients.

Perfected Monoclonal Antibody Platform

Skip to the good part! Get to the clinic and file with the FDA faster through our perfected platform for monoclonal antibody production. Cytovance has developed platform bioreactor processes for ThermoFisher’s Freedom™ CHO-S that let you bypass steps in the traditional manufacturing timeline. Additionally, Cytovance has a proven track record of developing processes for CHO-K1 and DG44 cell lines as well. With a suite of analytical methods and proven regulatory history, Cytovance is your mAb-based production partner.

Modern Assets to Support Product Advancement

Our Ingenuity Campus is equipped with state-of-the-art technology to enable fast and efficient development of your process. Cytovance has capabilities in batch and fed-batch bioreactor processes from scaled-down R&D to commercial-scale cGMP capacity.

Related Areas of Expertise

Cell Line Development

Complete mammalian clone selection, clonal stability, and banking services tailored to your requirements.

Mammalian Analytical Development

Robust analytical method development or transfer personalized for your mammalian-derived biologic.

Mammalian Manufacturing

Benefit from our full-service CGMP facility from cell banks to production with up to 2,000L capacity.